Draft:Hahahahahah

Teams and riders
All teams use series-specified Dunlop tyres and Triumph 765cc 3-cylinder engines.

Team changes

 * Forward Racing and MV Agusta ended their partnership which started in . Forward Racing entered the 2023 season using motorcycles under their own brand.

Rider changes

 * Dennis Foggia made his Moto2 debut with Italtrans Racing Team, replacing Lorenzo Dalla Porta.
 * Cameron Beaubier returned to the AMA Superbike Championship after two years in Moto2. Rory Skinner replaced Beaubier at American Racing, to make his full-time Moto2 debut, having appeared as a wildcard rider for the team in . Skinner raced in the British Superbike Championship in 2022.
 * Sergio García made his Moto2 debut with Pons Wegow Los40, replacing Jorge Navarro. Navarro then left Moto2 for the Supersport World Championship.
 * Álex Escrig made his Moto2 debut with Forward Team, replacing Simone Corsi who became the rider coach for the team. Escrig raced in both the MotoE World Cup and Moto2 European Championship in 2022.
 * Lorenzo Dalla Porta moved to Pertamina Mandalika SAG Team from Italtrans Racing Team, replacing the now-retired Gabriel Rodrigo.
 * Albert Arenas moved to Red Bull KTM Ajo from GasGas Aspar Team, replacing Augusto Fernández who moved up to MotoGP. Moto3 World Riders' Champion Izan Guevara then moved up from Moto3 while remaining with GasGas Aspar Team, replacing Arenas.
 * Kohta Nozane made his full-time debut with Correos Prepago Yamaha VR46 Master Camp, replacing Keminth Kubo. Nozane has raced before as a replacement rider in the Moto2 and MotoGP classest. Nozane raced in the Superbike World Championship in 2022.
 * Darryn Binder and Lukas Tulovic raced for Liqui Moly Husqvarna Intact GP, replacing Jeremy Alcoba and Marcel Schrötter. Alcoba moved to QJmotor Gresini Moto2, replacing Alessandro Zaccone, while Schrötter left Moto2 for the Supersport World Championship. Binder made his Moto2 debut, having raced in MotoGP in 2022. Tulovic, who is the 2022 Moto2 European Champion, returned to the Moto2 class, having last raced in . Tulovic also raced as a replacement rider in MotoE in 2022.
 * Borja Gómez made his full-time debut with Fantic Racing, replacing Niccolò Antonelli who was previously announced to race with the team in 2023, and was also included in the released provisional entry list. Gómez has served as a replacement rider in 2022.

Mid-season changes

 * Izan Guevara missed the first two rounds of the season due to a triangular fibrocartilage injury in his right wrist sustained during testing at Portimão. He was replaced by Jordi Torres.
 * Ai Ogura missed the Portuguese round after undergoing surgery on his left wrist that was injured during a training accident. He was not replaced.
 * Álex Escrig competed during P1 of the Portuguese round, but withdrew after being declared unfit due to the effects of a right shoulder injury sustained during pre-season testing. He was replaced by David Sanchis for the rest of the weekend, and also at the Argentine and Americas rounds. Escrig also missed the Italian, German, and Dutch rounds to continue his recovery. He was replaced by Lorenzo Dalla Porta for the Italian and German round, and by Yeray Ruiz for the Dutch round. Dalla Porta raced for Pertamina Mandalika SAG Team from the start of the season but parted ways with the team after the French round. He was replaced by Taiga Hada starting from the Italian round. Escrig also missed the Catalan, San Marino, Indian, and Japanese rounds after sustaining a fractured tibia during P3 of the previous Austrian round. He was again replaced by Ruiz for the Catalan round, and by Sean Dylan Kelly for the San Marino, Indian, and Japanese rounds. Kelly raced for American Racing from the start of the season but parted ways with the team after the Austrian round. He was replaced by Marcos Ramírez starting from the Catalan round.
 * Kohta Nozane missed seven Grands Prix due to a lower back injury sustained at the Portuguese round. He was replaced by Soichiro Minamimoto for the Argentine, Americas, and Spanish rounds, by Kasma Daniel for the Italian and German rounds, and was not replaced for the French and Dutch rounds.
 * Lukas Tulovic missed the Argentine round due to a previous injury which also caused him to withdraw from the previous Portuguese round. He was not replaced. He also missed the Japanese round due to a broken collarbone. He was replaced by Senna Agius.
 * Darryn Binder missed the Spanish and French rounds after suffering a double fracture of his right hand during P3 of the Americas round. He was replaced for both races by Senna Agius. Binder also missed the Catalan and San Marino rounds due to a fractured vertebrae sustained in a crash during the previous Austrian race. He was again replaced for both races by Agius.
 * Rory Skinner missed the German and Dutch rounds after suffering a fractured right foot during P3 of the Italian round. He was replaced for both races by Carlos Tatay.
 * Marcos Ramírez competed during P1 of the Dutch round, but withdrew after suffering a small fracture in his right elbow during the session. He was replaced for the rest of the weekend by Álex Escrig. Escrig is a regular rider and Ramírez's teammate. He was initially declared unfit for the Dutch round and was replaced by Yeray Ruiz. Eventually, Escrig was declared fit enough to serve as a replacement rider for Ramírez.
 * Sean Dylan Kelly missed the British and Austrian rounds to continue his recovery from forearm surgery after being plagued with arm pump issues. He was not replaced for the British round, and was replaced by Marcos Ramírez for the Austrian round. Ramírez raced for Forward Team from the start of the season but parted ways with the team after the British round. He was replaced by Alberto Surra starting from the Austrian round. Kelly parted ways with the team after the Austrian round. He was replaced by Ramírez as a full-time rider starting from the Catalan round.
 * Taiga Hada missed the Austrian and Catalan rounds due to injury. He was replaced for both races by Mattia Rato.
 * Celestino Vietti missed the Japanese and Indonesian rounds due to a fractured pubic bone sustained in the Indian race. He was replaced by Borja Gómez for the Japanese round, and by Lorenzo Baldassarri for the Indonesian round. Gómez raced for Fantic Racing from the start of the season as a regular rider and was Vietti's teammate but parted ways with the team after the Indian round. He was replaced by Mattia Casadei as a full-time rider starting from the Japanese round.
 * Alberto Surra missed the Malaysian round due to injury. He was replaced by Sean Dylan Kelly.