Draft:Nawin Mishra

Nawin Chandra Mishra is an Indian genetics educator and an Emeritus Professor of Molecular Genetics and Genomics in the Department of Biological Sciences at the University of South Carolina.

Education
Dr. Mishra completed Ph.D. from McMaster University in 1967.

Dr. Mishra received his post-doctoral training with the late Nobel Laureate Professor E. L. Tatum at Rockefeller University as a Fellow for Medical Research of the Jane Coffin Child Fund for two years and then as a Research Associate with Professor Tatum, where he initiated his work in what is now called as Proteomics and Metabolomics.

Career
From 1967-1969, he was a medical research fellow at Rockefeller University, New York City.

He was as an associate professor at the University of South Carolina Molecular Biology Group.

In 1980, he was as a visiting professor at the Max Planck Institute for Molecular Biology in Heidelberg, Germany, and in 2004 at the Genetic Institute of Greenwood, SC. In 2000, he served as a member of the human genome project review panel, United States Department of Energy.

He was also the science advisor to the FAO (Food and Agriculture Organization) of the United Nations in India.

Contribution to science

 * Correlation of genes and enzymes, which initiated the infancy of proteomics.
 * Development of first gene transfer in eukaryotes.
 * Elucidation of DNA replication and repair by creating mutants and their characterization.
 * First report of the presence of Beta DNA polymerase in lower eukaryotes like Neurospora crassa.
 * First DNA sequencing of a major part of the mitochondrial DNA of Neurospora.

Books

 * Introduction to Proteomics: Principles and Applications (Methods of Biochemical Analysis Book 146) 2010. John Wiley & Sons, New York- ISBN 978-0471754022
 * Nucleases: Molecular Biology and Applications. 1995 Cell Press, Boca Raton, Fl. – ISBN 978-0471394617
 * Nucleases 2002 John Wiley and Sons, New York. - ISBN 0-471- 39461-0
 * Sciences of Multiomics 2024 Springer – Nature press

Articles

 * Mishra NC 1977. Genetics and Biochemistry of Morphogenesis in Neurospora Advances in Genetics 19: 341-407.
 * Mishra NC. 1985. Gene Transfer in Fungi. Advances in Genetics 23: 74-178.
 * Mishra NC .1991. Genetics and Molecular Biology of Neurospora crassa. Advances in Genetics .29: 2-62
 * Mishra N C .2012 Sciences of Proteomics: Historical Perspectives and Possible Role in Human Health Care. Pharmaceutical Production Technology.10.485- 509.
 * Mishra N C. 2016.Science of Omics: Historical Perspectives and Role in Human Health Care. Integrative Molecular Medicine. 2017. 3. 1-8
 * Mishra NC 1967.Genetic Studies in Neurospora and Eudorina. Ph. D. Thesis. McMaster University, Hamilton, Canada.
 * *Mishra NC and SFH Threlkeld. 1967. Variation in the expression of rg mutants in Neurospora. Genetics 55, 113-121.
 * Mishra NC 1971. Heterokaryiosis in Neurospora sitophila. Genetics 67, 55- 59
 * Mishra N C and E.L. Tatum. 1970a. Phosphoglucomutase mutants of Neurospora sitophila. Proc. National. Academy of Sciences USA. 60, 638-645
 * Mishra N C and E.L. Tatum 1970b. Pleiotropy of gene mutations in Neurospora J. Cell Biology. 470. 141
 * Mishra N C and E.L. Tatum 1972. Effect of L-sorbose on the polysaccharide synthetase of Neurosora and its relation to morphology. Proc. National Acad. Sciences USA 60. 638-645
 * Mishra NC and E.L. Tatum 1973 Non-Mendelian inheritance of inositol-independence in Neurospora. Proc. National. Academy of Sciences USA70.3875-3879.
 * Mishra NC, M. C. Niu, and E.L. Tatum 1975 Induction by RNA of inositol independence in Neurospora. Proc National Academy of Sciences.72. 462-465
 * Mishra NC, Szabo G. and E.L. Tatum1973 Nucleic Acid Changes in Neurospora. In the Role of RNA in Reproduction and Development (M.C. Niu and S. Segal) 259-268 North Holland Publisher, Amsterdam
 * Cooley M, Mishra NC. (2000) "Genetic analysis of the in vivo role of DNA polymerases in Saccharomyces cerevisiae Current Genetics." 38: 256-263
 * Singleton RW, Mishra NC. (1995) "Genetic evidence that aphidicolin inhibits in vivo DNA synthesis in Chinese hamster ovary cells." Molecular & General Genetics: Mgg. 247: 462-70
 * Fehér Z, Mishra NC. (1995) "An aphidicolin-resistant mutant of Chinese hamster ovary cell with altered DNA polymerase and 3' exonuclease activities." Biochimica Et Biophysica Acta. 1263: 141-6
 * Fehér Z, Mishra NC. (1994) "Aphidicolin-resistant Chinese hamster ovary cells possess altered DNA polymerases of the alpha family." Biochimica Et Biophysica Acta. 1218: 35-47
 * Almasan A, Mishra NC. (1991) "Recombination by sequence repeats with the formation of suppressive or residual mitochondrial DNA in Neurospora." Proceedings of the National Academy of Sciences of the United States of America. 88: 7684-8
 * Niagro FD, Mishra NC. (1990) "Biochemical, genetic and ultrastructural defects in a mitochondrial mutant (ER-3) of Neurospora crassa with senescence phenotype." Mechanisms of Ageing and Development. 55: 15-37
 * Almasan A, Mishra NC. (1990) "Characterization of a novel plasmid-like element in Neurospora crassa derived mostly from the mitochondrial DNA." Nucleic Acids Research. 18: 5871-7
 * Mishra NC, Almasan A, Cooley M. (1990) "Characterization of eukaryotic DNA polymerases: aphidicolin resistant mutants of Neurospora with altered DNA polymerase." Progress in Clinical and Biological Research. 344: 295-313
 * Niagro FD, Mishra NC. (1989) "An ethidium bromide-induced mutant of Neurospora crassa defective in mitochondrial DNA." Current Genetics. 16: 303-5
 * Almasan A, Mishra NC. (1988) "Molecular characterization of the mitochondrial DNA of a new stopper mutant ER-3 of Neurospora crassa." Genetics. 120: 935-45