E300

E300 or E-300 may refer to:
 * Alexander Dennis Enviro300, a popular British bus built upon various chassis
 * Brandner E-300, an Egyptian turbojet engine
 * HB-E300 series, a Japanese hybrid diesel train type
 * Olympus E-300, a digital camera manufactured by Olympus
 * PowerPC e300, a family of microprocessor cores
 * Ascorbic acid, a compound numbered E300 in the European food additive E number system
 * Eurostar e300, a class of Eurostar passenger trains also known as British Rail Class 373 and TGV TMST
 * Extra 300, an acrobatic monoplane