E38

E38 or E-38 may refer to:
 * BMW E38, a BMW 7 Series automobile
 * HMS E38, a 1916 British E class submarine
 * Hikarigaoka Station or E-38, a Tokyo Toei Ōedo Line railway station
 * Nimzo-Indian Defence or E38, a chess opening
 * Alpine–Casparis Municipal Airport, an airport in Texas having the FAA LID code of E38.
 * European route E38 in Ukraine, Russia and Kazakhstan
 * Dōtō Expressway (main route) and Kushiro Sotokan Road (between Kushiro-nishi IC and Kushiro-higashi IC), route E38 in Japan
 * SMART Tunnel, route E38 in Malaysia