E41

E41, E-41 or E.41 may refer to:
 * HMS E41, a United Kingdom Royal Navy E-class submarine which saw service during World War I
 * European route E41, a road in Germany and Switzerland
 * DB Class E 41, a locomotive manufactured in Germany
 * Nimzo-Indian Defense, Encyclopaedia of Chess Openings code
 * Tōkai-Hokuriku Expressway and Nōetsu Expressway, route E41 in Japan
 * Long Win Bus Route E41 in Hong Kong