E450

E450 or E-450 may refer to:


 * E450 (food additive)
 * E-450, a Ford E-Series van or minibus
 * Olympus E-450, a camera
 * ThinkPad E450, laptop
 * E450, a model variant of the Mercedes-Benz E-Class (W213)
 * E-450, an AMD processor with 3D graphics
 * E450 series, a Sony Walkman digital audio player, see Walkman E Series