ESM

ESM may refer to:

Education

 * Eastman School of Music, in Rochester, New York, United States
 * Eastport-South Manor Central School District, in New York, United States
 * East Syracuse-Minoa Central School District, in New York, United States
 * East Syracuse-Minoa High School, in Manlius, New York, United States
 * École secondaire de Mirabel, a secondary school in Quebec, Canada
 * École spéciale militaire de Saint-Cyr, a French military academy
 * Emmanuel School of Mission
 * Engineering science and mechanics
 * European School, Munich, in Germany

Science and technology

 * Earth System Model
 * ECMAScript Modules
 * Electronic support measures
 * Embedded System Module
 * End System Multicast, a research project at Carnegie Mellon University
 * Energy Saving Module
 * Enterprise systems management
 * Ethosuximide, an antiepileptic drug
 * European Service Module, part of the Orion spacecraft
 * Event sampling methodology
 * Experience sampling method

Transport

 * Colonel Carlos Concha Torres Airport, serving Esmereldas, Ecuador
 * Elsenham railway station, in England
 * Essex station (Montana), a train station in the United States

Other uses

 * Elektrani na Severna Makedonija (Електрани на Северна Македонија), a power company in North Macedonia
 * Election stock market
 * Emergency Services Medal (Australia)
 * Enterprise service management
 * Esuma language
 * Eurasian Youth Union, a Russian political organisation
 * European Single Market
 * European Social Movement, a defunct neo-fascist organisation
 * European Sports Media
 * European Stability Mechanism
 * European Supermarket Magazine
 * Extreme Speed Motorsports, an American auto racing team
 * Enterprise Securities Market, a market of the Irish Stock Exchange