Earlham Institute

Earlham Institute (EI, formerly The Genome Analysis Centre (TGAC) ) is a life science research institute located at the Norwich Research Park (NRP), Norwich, England. EI's research is focused on exploring living systems by applying computational science and biotechnology to answer ambitious biological questions and generate enabling resources.

History
The institute was established by the Biotechnology and Biological Sciences Research Council in partnership with East of England Development Agency (EEDA), Norfolk County Council, Norwich City Council, South Norfolk Council and the Greater Norwich Development Partnership. It cost £13.5 million, and was built by Morgan Sindall. It was officially opened on 3 July 2009 by John Sulston, winner of the 2002 Nobel Prize in Physiology or Medicine, and former Director of the Wellcome Trust Sanger Institute, another genomics research institution.

In early June 2011, it unveiled a supercomputer on its site that has the most powerful processor in the world that runs Red Hat Linux, with six terabytes of RAM. It was installed to crack the structure of the wheat genome, which is five times larger than the human genome.

In June 2016, Earlham Institute completed a rebranding project which saw the name transition from The Genome Analysis Centre (TGAC) to Earlham Institute (EI).

Structure
It is situated on the Norwich Research Park, to the west of Norwich on the former A47 (B1108), and adjacent to the west of the University of East Anglia, next to the River Yare.

Function
The goal of this institute is to be at the forefront of data intensive science in biology, to be a leader in bioinformatics innovation and the application of genome technology and to enable bioscience through dissemination of the data and technology produced in the institute and in collaboration with external scientists worldwide. Project specialisms include wheat and ryegrass, but the wider research carried out includes vertebrate, evolutionary, environment, and regulatory genomics as well as data infrastructure and software development to support the international bioscience community. EI makes its research open access where possible.

Directors
Earlham Institute has been directed by:
 * Jane Rogers from July 2009 to December 2012;
 * Mario Caccamo from January 2013 to July 2015;
 * Dylan Edwards from August 2015 (Interim Director)
 * Neil Hall from April 2016 (Current Director)

Communicating science
One of the responsibilities of EI is to communicate the science it undertakes to a range of audiences, such as the international scientific community, the general public, school children, and students. It runs various programmes throughout the year to deliver this responsibility, as well as producing editorial features to explain the research it carries out.

Facilities
EI has a state-of-the-art scientific training facility which helps support the delivery of workshops and training courses to support the international bioscience community.

Sequencing platforms
EI is equipped with next-generation sequencing and genomics platforms for high-throughput data generation for research projects. EI historically has been an early adopter of new technologies for its scientific research, but also makes these available to the UK bioscience community through its National Capability in Genomics.


 * Illuina NovaSeq
 * Illumina HiSeq 2500
 * Illumina MiSeq
 * Illumina iSeq100
 * PacBio Sequel
 * PacBio Sequel II
 * Oxford Nanopore MinION
 * Oxford Nanopore GridION
 * 10X Chromium

Pandemic support
Scientists at Earlham Institute and Quadram Institute are helping to develop a new tool to translate the dynamic microbiome/body communication. The method would be useful to researchers seeking to learn how microbes impact safety, the modifications contributing to illness, and pointing to new targets for medicines.