Early myoclonic encephalopathy

Early myoclonic encephalopathy (EME) is a rare neonatal-onset epilepsy developmental and epileptic encephalopathy (DEE) with an onset at neonatal period or during the first 3 months of life. This syndrome is now included as part of the Early infantile developmental and epileptic encephalopathy (EIDEE) under the 2022 ILAE (International League Against Epilepsy) syndrome classification.

Epidemiology
The prevalence estimates among EME are of <1 / 1 000 000.