East Main Street–Douglass Heights Historic District

East Main Street–Douglass Heights Historic District is a national historic district located at Union, Union County, South Carolina. The district encompasses 55 contributing buildings in a primarily residential section of Union. The houses were built between about 1823 to 1940, and are in a variety of popular architectural styles include Neo-Classical, Queen Anne, and Colonial Revival. Notable dwellings include the Steadman-Nicholson House, Laurens G. Young House, and William H. Wallace House. Located in the district is the separately listed Union High School-Main Street Grammar School.

It was added to the National Register of Historic Places in 1989.