Espe

Espe may refer to:


 * Escuela Politécnica del Ejército, also called ESPE, a higher education university in Sangolquí, Ecuador
 * Espe (Fulda), a river in Hesse, Germany, tributary of the Fulda
 * Espe (manor house), a historic estate in Boeslunde, Slagelse Municipality, Denmark
 * Vidsel Air Base, ICAO airport code ESPE, a Swedish Air Force airfield located near Vidsel
 * Espe, Denmark, a village on the island Funen, Denmark
 * Espe, Norway, a village in the county of Hordaland, Norway, see list of villages in Hordaland
 * Aaron Espe (born 1981), American singer-songwriter, instrumentalist and record producer