F16 (disambiguation)

F16, F 16, F-16 or FI6 may refer to:
 * General Dynamics F-16 Fighting Falcon, a 1974 American multirole fighter jet aircraft
 * FI6 (antibody), an antibody that targets influenza A viruses
 * F 16 Uppsala, a Swedish air force base
 * Formula 16, a 5-metre catamaran
 * Nacra F16 a Formula 16 catamaran design
 * Volvo F16, a truck
 * Half-precision floating-point format, a 16-bit computer number format
 * Shibuya Station, a railway station in Tokyo, coded as F16 on the Fukutoshin Line
 * Fluorine-16 (F-16 or 16F), an isotope of fluorine