FRB

FRB may refer to:
 * Fast radio burst in radio astronomy
 * Fractional-reserve banking
 * Fairbourne railway station, in Wales, station code
 * Federal Reserve Board of Governors, in the United States
 * Federal Reserve Bank
 * Forbes Airport, New South Wales, Australia, IATA code
 * Team Frøy–Bianchi, a Norwegian cycling team, code
 * FKBP12-Rapamycin Binding domain; see Mechanistic target of rapamycin