Fall 2021 Chicago House AC season

The Fall 2021 Chicago House AC season was the club's first in the National Independent Soccer Association and first as a professional team.

NISA Independent Cup
Details for the 2021 NISA Independent Cup were released on June 10.

National Independent Soccer Association season
Details regarding the Fall season were released on June 16.

Appearances and goals
! colspan="14" style="background:#dcdcdc; text-align:center"| Goalkeepers

! colspan="14" style="background:#dcdcdc; text-align:center"| Defenders

! colspan="14" style="background:#dcdcdc; text-align:center"| Midfielders

! colspan="14" style="background:#dcdcdc; text-align:center"| Forwards


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