File:Pyroptosis pathways 2.png

Summary
Canonical, noncononical and caspase-3 dependent pyroptotic pathways Triggered by PAMPs or DAMPs stimulation, create gasdermin pores on cell membrane, cell lysis

Modified from Fig.1, Fang, Yuan; Tian, Shengwang; Pan, Yutian; Li, Wei; Wang, Qiming; Tang, Yu; Yu, Tao; Wu, Xi; Shi, Yongkang; Ma, Pei; Shu, Yongqian (January 2020). "Pyroptosis: A new frontier in cancer". Biomedicine & Pharmacotherapy. 121: 109595. doi:10.1016/j.biopha.2019.109595