First Presbyterian Church (Keytesville, Missouri)

First Presbyterian Church is a historic Presbyterian church located at Hill and East Streets in Keytesville, Chariton County, Missouri. It was built in 1853, and is a one-story, Classical Revival style frame building with a turn-of-the-20th century Romanesque Revival derivative style addition. It features a two-story plus belfry tower.

It was listed on the National Register of Historic Places in 1977.