First degree

First degree may refer to:
 * An undergraduate degree or a first professional degree
 * First Degree, a drama series
 * First-degree black belt (martial arts), a proficiency level earned in martial arts
 * First-degree murder
 * A first-degree burn
 * First-degree price discrimination
 * First-degree atrioventricular block, a disease of the electrical conduction system of the heart
 * Parent/offspring or sibling (first-degree relative)
 * A first cousin (third-degree relative)
 * The First Degree, a 1923 American film directed by Edward Sedgwick starring Frank Mayo