Flight 422

Flight 422 may refer to:


 * Air France Flight 422, a flight which crashed near Bogotá, Colombia, in 1998
 * Kuwait Airways Flight 422, a flight hijacked over the Gulf of Oman in 1988, leading to one of the longest skyjackings on record
 * Merpati Nusantara Airlines Flight 422, a 1994 flight that overshot the runway at Indonesia's Achmad Yani International Airport