Francis I

Francis I or Francis the First may refer to:


 * Francesco I Gonzaga (1366–1407)
 * Francis I, Duke of Brittany (1414–1450), reigned 1442–1450
 * Francis I of France (1494–1547), King of France, reigned 1515–1547
 * Francis I, Duke of Saxe-Lauenburg (1510–1581), reigned 1543–1571
 * Francis I, Duke of Nevers (1516–1561), reigned 1539–1561
 * Francis I, Duke of Lorraine (1517–1545), reigned 1544–1545
 * Francesco I de' Medici, Grand Duke of Tuscany (1541–1587), reigned 1574–1587
 * Francis I of Beauharnais (died 1587), leading noble of the French House of Beauharnais
 * Francesco I d'Este, Duke of Modena (1610–1658), reigned 1644–1658
 * Francis I Rákóczi (1645–1676), elected prince of Transylvania
 * Francis I, Holy Roman Emperor (1708–1765), reigned 1745–1765
 * Francis I (Erbach-Erbach) (1754–1823), Count of Erbach
 * Francis I of the Two Sicilies (1777–1830), reigned 1825–1830
 * Francis II, Holy Roman Emperor, also known as Francis I, Emperor of Austria, (1768–1835), reigned 1804–1835
 * Franz I, Prince of Liechtenstein (1853–1938)
 * Pope Francis (born 1936), leader of the Catholic Church since 2013
 * Francis the First (play), an 1832 play by Fanny Kemble
 * Francis the First (film), a 1937 French historical comedy film
 * Francis the First, an opera composed by Edward Loder