Francis II

Francis II may refer to:


 * Francis II, Duke of Brittany (1433–1488)
 * Francesco II Gonzaga, Marquess of Mantua (1466–1519), ruler of the Italian city of Mantua
 * Francis II of France (1544–1560), king of France
 * Francis II, Duke of Lorraine (1572–1632), son of Charles III, Duke of Lorraine, and Claude of Valois
 * Francesco II d'Este, Duke of Modena (1660–1694)
 * Francis II Rákóczi (1676–1735), Prince of Transylvania
 * Francis II, Holy Roman Emperor (1768–1835), last Holy Roman Emperor
 * Francis II of the Two Sicilies (1836–1894), last king of the Two Sicilies
 * Franz, Duke of Bavaria (born 1933), called "Francis II" by supporters of the Jacobite claim to the thrones of England, Scotland, Ireland, and France
 * Francis II, Duke of Saxe-Lauenburg (1547–1619), third son of Francis I of Saxe-Lauenburg and Sybille of Saxe-Freiberg