Francis O'Brien

Francis or Fran O'Brien may refer to:

Politics

 * Francis O'Brien (Canadian politician) (born 1927), Canadian politician and farmer
 * Francis O'Brien (Irish politician) (born 1943), Irish Fianna Fáil politician

Sport

 * Francis O'Brien (cricketer) (1911–1991), New Zealand cricketer
 * Fran O'Brien (American football) (1936–1999), American National Football League player
 * Fran O'Brien (footballer) (born 1955), Irish footballer

Other

 * Francis O'Brien, executive producer of Gallipoli (1981 film)