Francisco León

Francisco León may refer to:


 * Francisco León, Chiapas, a town and municipality of Chiapas, Mexico
 * Francisco León (Mister Venezuela) (born 1981), Venezuelan model and singer
 * Francisco Giovanni León (born 1992), Mexican footballer
 * Francisco Herrera León (born 1966), Mexican politician
 * Francisco León Franco (1832–1880), Vice President of Ecuador
 * Francisco León Mane (born 1973), Spanish cyclist