Frank Clayton

Frank Clayton may refer to:

People

 * Frank Clayton (Otago cricketer) (1866–1944), New Zealand cricketer
 * Frank Clayton (Canterbury cricketer) (1866–1941), New Zealand cricketer
 * Frank Clayton (American football) in 1955 NFL Draft

Fictional characters

 * Frank Clayton (Emmerdale), fictional character from the British soap opera Emmerdale
 * Frank Clayton, character in Saratoga (film)
 * Frank Clayton, character in Pleasures of the Rich