Frank Henderson

Frank Henderson may refer to:


 * Frank Henderson (cricketer) (1908–1954), Australian cricketer
 * Frank Henderson (poker player) (born 1931), American poker player
 * Frank Henderson (public servant) (1911–1969), Australian public servant
 * Frank Henderson (Scottish politician) (1836–1889), Scottish Liberal politician
 * Frank Henderson (South Dakota politician) (1928–2012), American politician from South Dakota
 * Frank Henderson (Idaho politician) (1922–2015), Republican Idaho state representative
 * Frank Henderson (footballer) (1900–1966), English football left half
 * Frank Henderson (Irish revolutionary) (1886–1959), captain in the Irish Volunteers