Frank Holmes

Frank Holmes may refer to:


 * Sir Frank Holmes (economist) (1924–2011), New Zealand economist
 * Frank Holmes (geologist) (1874–1947), British geologist
 * Frank E. Holmes, chief executive and chief investment officer at U.S. Global Investors
 * Frank Holmes (athlete) (1885–1980), American track and field athlete
 * Frank J. Holmes, American painter
 * Frank Holmes (filmmaker) (1908–1990), producer and director of Seaport of the Prairies
 * Frank Holmes (footballer) (1900–1989), Australian rules footballer
 * Frankie Holmes, a co-host and subject of the documentary television series Dopesick Nation