Frank Powell (disambiguation)

Frank Powell was a stage and silent film actor, screenwriter and director in the United States.

Frank Powell may also refer to:
 * David Franklin Powell (1847–1906), also known as D. Frank Powell, Wisconsin doctor, showman, patent medicine magnate and politician
 * Frank John Powell (1891–1971), British politician and magistrate
 * Frank Powell (footballer), English football manager
 * Frank Neff Powell, bishop of the Episcopal diocese of Southwestern Virginia