GWC

GWC may refer to:


 * Dutch West India Company (Dutch: Geoctroyeerde Westindische Compagnie)
 * Gambian Workers' Confederation, a Gambian trade union
 * General Watch Co, a defunct Swiss watchmaker
 * George Watson's College, in Edinburgh, Scotland
 * George Whitefield College, in Cape Town, South Africa
 * George Wythe College, now George Wythe University, in Salt Lake City, Utah, United States
 * Global Wildlife Center, a conservation charity
 * Gnome Wave Cleaner, audio software
 * Golden West College, in Huntington Beach, California, United States
 * Government Wine Cellar, of the government of the United Kingdom
 * Great Wall of China, a series of fortifications
 * Great West Conference, an American college athletic conference
 * The Great Western Chorus of Bristol, a British choir
 * Green–white–checker finish, a procedure in North American auto racing
 * Green Worker Cooperatives, a worker cooperative incubator in New York City
 * Kalami language, spoken in Pakistan