Giacomo Orsini

Giacomo Orsini or Jacopo Orsini may refer to:


 * Giacomo Orsini (cardinal) (1340–1379)
 * Giacomo Orsini, Count of Tagliacozzo (died 1431)
 * Jacopo Orsini, Lord of Monterotondo (1424–1482)
 * Giacomo Orsini (bishop) (fl. 1497–1530)