Glucarate dehydratase

The enzyme glucarate dehydratase catalyzes the chemical reaction


 * D -glucarate $$\rightleftharpoons$$ 5-dehydro-4-deoxy- D -glucarate + H2O

This enzyme belongs to the family of lyases, specifically the hydro-lyases, which cleave carbon-oxygen bonds. The systematic name of this enzyme class is  D -glucarate hydro-lyase (5-dehydro-4-deoxy- D -glucarate-forming). Other names in common use include  D -glucarate dehydratase, and  D -glucarate hydro-lyase. This enzyme participates in ascorbate and aldarate metabolism.

Structural studies
As of late 2007, 7 structures have been solved for this class of enzymes, with PDB accession codes, , , , , , and.