Great Southern

Great Southern may refer to:


 * Great Southern (automobile), a car in production from 1910 to 1914
 * Great Southern (band), the backing band for American rock guitarist Dickey Betts
 * Great Southern (train), a luxury train service in Australia
 * Great Southern (Western Australia), a region in Western Australia
 * Great Southern (wine region), in Western Australia
 * Great Southern Group, a corporate group in Australia which collapsed in 2009
 * Great Southern Television, based in Auckland and Sydney
 * TSS Great Southern (1902), a ship built in 1902 for the Great Western Railway
 * Great Southern Bank, Australian bank