Guadiana (disambiguation)

Guadiana may refer to:


 * Guadiana, a river in southern Spain and Portugal
 * Ojos del Guadiana
 * Guadiana Valley Natural Park, a natural park in southeastern Portugal
 * Guadiana International Bridge
 * Guadiana, Naranjito, Puerto Rico, a barrio of Naranjito, Puerto Rico
 * Guadiana, Badajoz, a town and municipality in Extremadura, Spain (formerly Guadiana del Caudillo)
 * Guadiana River (Puerto Rico), a river in Puerto Rico
 * Guadiana Bay, a bay in western Cuba
 * Ribera del Guadiana, a Spanish protected designation of origin (Denominación de Origen - DO) for wines in Extremadura
 * Guadiana Trophy, an annual football (soccer) tournament hosted by Portugal and played in the pre-season