Guanosine-3',5'-bis(diphosphate) 3'-diphosphatase

The enzyme guanosine-3′,5′-bis(diphosphate) 3′-diphosphatase (EC 3.1.7.2) catalyzes the reaction


 * guanosine 3′,5′-bis(diphosphate) + H2O $$\rightleftharpoons$$ GDP + diphosphate

This enzyme belongs to the family of hydrolases, specifically those acting on diphosphoric monoester bonds. The systematic name is guanosine-3′,5′-bis(diphosphate) 3′-diphosphohydrolase. Other names in common use include guanosine-3′,5′-bis(diphosphate) 3′-pyrophosphatase, PpGpp-3'-pyrophosphohydrolase, and PpGpp phosphohydrolase. This enzyme participates in purine metabolism.

Structural studies
As of late 2007, only one structure has been solved for this class of enzymes, with the PDB accession code.