Guardian II

Guardian II or Guardians 2, may refer to:


 * Guardians of the Galaxy Vol. 2 (film) aka "Guardians 2", a 2017 film set in the Marvel Cinematic Universe
 * Guardians of the Galaxy Volume 2 (book) aka "Guardians, volume 2", a Marvel Comics compilation comic book; see Guardians of the Galaxy (2008 team)
 * Guardian II: Revenge of the Mutants (videogame), a 1990 videogame; see List of Amstrad CPC games and List of ZX Spectrum games
 * Guardian II (character), a DC Comics character; see List of Young Justice characters
 * Guardian II (character), a Marvel Comics character; see Official Handbook of the Marvel Universe
 * Operation Guardian II (military operation), a 2002 Royal Australian Air Force operation
 * McCoy Miller Guardian II (vehicle), an ambulance type operated by the Lancaster Volunteer Ambulance Corps