Guillermo Rodríguez

Guillermo Rodríguez may refer to:


 * Guillermo Rodríguez (baseball), Venezuelan baseball catcher
 * Guillermo Rodríguez (footballer), Uruguayan footballer
 * Guillermo Rodríguez (athlete), Mexican Olympic sprinter
 * Guillermo Rodríguez (politician), also known as Guillermo Rodríguez Lara, Ecuadorian politician
 * Guillermo Rodríguez González, Spanish archer
 * Guillermo Rodriguez (comedian), Recurring cast member of Jimmy Kimmel Live!