H50

H50 may refer to:

Television

 * Hawaii Five-O (1968 TV series), a police procedural drama set in Hawaii, originally aired from 1968 to 1980
 * Hawaii Five-0 (2010 TV series), the 2010 remake of Hawaii Five-O

Vehicles

 * HMS H50, a 1920 British Royal Navy H class submarine
 * QH-50 DASH, a U.S. Navy unmanned anti-submarine helicopter
 * H50, the third generation of Toyota HiAce

Other

 * DSC-H50, a 2008 Sony 9.1 megapixel Cyber-shot H series camera
 * ICD-10 code for strabismus