HCE

HCE may refer to:
 * HCE (car), a British cyclecar
 * Humboldt Current ecosystem
 * Choriolysin H, an enzyme
 * Harvey Comics Entertainment
 * Hawaii Creole English language
 * Hexachloroethane
 * Hierarchical Cluster Engine Project
 * Host card emulation
 * RNGTT, a protein
 * Humphrey Chimpden Earwicker, a character in James Joyce's novel Finnegans Wake
 * Halo: Combat Evolved