HFB

HFB may refer to:


 * Hafnium boride (HfB)
 * Hamburger Flugzeugbau, German aircraft manufacturer
 * Harry F. Byrd, a prominent US Senator from Virginia
 * Hexafluorobenzene, an aromatic organofluoride
 * Hexafluoro-2-butyne, an alkyne organofluoride
 * Hindu Forum of Britain
 * Hochschule für Bankwirtschaft (HfB), now part of the Frankfurt School of Finance & Management
 * Housing Finance Bank, Uganda
 * Houston Food Bank