HGPS

HGPS may refer to:
 * Progeria (Hutchinson–Gilford progeria syndrome)
 * Hellisheiði Power Station, in Iceland
 * Holy Ghost Preparatory School, in Bensalem, Pennsylvania, United States
 * Hospital General de la Plaza de la Salud in the Dominican Republic
 * LMNA, or Lamin A/C, a protein
 * ROBO3, or Roundabout homolog 3, a protein