HPR

HPR may refer to:
 * Handley Page (Reading)
 * HPR (gene)
 * Harvard Political Review
 * Hawaii Public Radio
 * Heartland Public Radio
 * HPR1, Heparanase
 * High-power rocketry
 * Highly Protected Risk in insurance; see FM Global
 * Holding period return
 * IBM Home Page Reader, spoken web browser
 * Homiletic and Pastoral Review
 * Hornsdale Power Reserve, a large battery in Australia
 * Host plant resistance
 * Hungarian People's Republic
 * Pointing dog