HSHS

HSHS may refer to:
 * Hamilton Southeastern High School, Fishers, Indiana, United States
 * Helensvale State High School, Helensvale, Queensland, Australia
 * Henry-Senachwine High School, Henry, Illinois, United States
 * Highland Springs High School, Highland Springs, Virginia, United States
 * Hinsdale South High School, Darien, Illinois, United States
 * Holy Spirit High School (disambiguation)
 * Holly Springs High School, Holly Springs, North Carolina, United States
 * Hot Springs High School (Arkansas), Hot Springs, Arkansas, United States
 * Hot Springs High School (Montana), Hot Springs, Montana, United States
 * Hospital Sisters Health System, Springfield, Illinois, United States