Haplogroup S (mtDNA)

In human genetics, Haplogroup S is a human mitochondrial DNA (mtDNA) haplogroup found only among Indigenous Australians. It is a descendant of macrohaplogroup N.

Origin
Haplogroup S mtDNA evolved within Australia between 64,000 and 40,000 years ago (51 kya).

Distribution
It is found in the Indigenous Australian population. Haplogroup S2 found in Willandra Lakes human remain WLH4 dated back Late Holocene (3,000–500 years ago).

The following table lists relevant GenBank samples:

Tree
This phylogenetic tree of haplogroup S subclades is based on the paper by Mannis van Oven and Manfred Kayser Updated comprehensive phylogenetic tree of global human mitochondrial DNA variation and subsequent published research. The TMRCA for haplogroup S is between 49 and 51 KYA according to Nano Nagle's Aboriginal Australian mitochondrial genome variation – an increased understanding of population antiquity and diversity publication that published in 2017.


 * S (64-40 kya) in Australia
 * S1 (53-32 kya) in Australia
 * S1a (44-29 kya) found in WA, NT, QLD and NSW
 * S1b (37-22 kya) found in NT, QLD and NSW
 * S1b1 (30-10 kya) found in NT and QLD
 * S1b1a (24-6 kya) found in QLD
 * S1b2 (17-3 kya) found in QLD
 * S1b3 (20-4 kya) found in QLD and NSW
 * S2 (44-22 kya) in Australia
 * S2a (38-18 kya) found in NT, QLD, NSW and TAS
 * S2a1 (31-12 kya) found in NSW, QLD and TAS
 * S2a1a (19-6 kya) found in NSW and QLD
 * S2a2 (38-11 kya) found in NT, QLD and NSW
 * S2b (42-18 kya) found in WA, NT, QLD and VIC
 * S2b1(27-9 kya) found in NT, QLD and VIC
 * S2b2 (37-12 kya) found in WA, NT and QLD
 * S3 (17-1 kya) found in NT
 * S4 found in NT
 * S5 found in WA
 * S6 found in NSW