Harmony School, School District No. 53

Harmony School, School District #53, built in 1879, is an historic Carpenter Gothic-style country one-room schoolhouse located in rural Otoe County, Nebraska, United States, near Nebraska City. The building was used for its intended purpose until 1997 when it was closed. It is now privately owned.

On July 22, 2005, Harmony School was added to the National Register of Historic Places.