Hematologic disease

Hematologic diseases are disorders which primarily affect the blood and blood-forming organs. Hematologic diseases include rare genetic disorders, anemia, HIV, sickle cell disease and complications from chemotherapy or transfusions.

Myeloid

 * Hemoglobinopathies (congenital abnormality of the hemoglobin molecule or of the rate of hemoglobin synthesis)
 * Sickle cell disease
 * Thalassemia
 * Methemoglobinemia
 * Anemias (lack of red blood cells or hemoglobin)
 * Iron-deficiency anemia
 * Megaloblastic anemia
 * Vitamin B12 deficiency
 * Pernicious anemia
 * Folate deficiency
 * Hemolytic anemias (destruction of red blood cells)
 * Genetic disorders of RBC membrane
 * Hereditary spherocytosis
 * Hereditary elliptocytosis
 * Congenital dyserythropoietic anemia
 * Genetic disorders of RBC metabolism
 * Glucose-6-phosphate dehydrogenase deficiency (G6PD)
 * Pyruvate kinase deficiency
 * Immune mediated hemolytic anemia (direct Coombs test is positive)
 * Autoimmune hemolytic anemia
 * Warm antibody autoimmune hemolytic anemia
 * Idiopathic
 * Systemic lupus erythematosus (SLE)
 * Evans syndrome (antiplatelet antibodies and hemolytic antibodies)
 * Cold autoimmune hemolytic anemia
 * Cold agglutinin disease
 * Paroxysmal cold hemoglobinuria (rare)
 * Infectious mononucleosis
 * Alloimmune hemolytic anemia
 * Hemolytic disease of the newborn (HDN)
 * Rh disease (Rh D)
 * ABO hemolytic disease of the newborn
 * Anti-Kell hemolytic disease of the newborn
 * Rhesus c hemolytic disease of the newborn
 * Rhesus E hemolytic disease of the newborn
 * Other blood group incompatibility (RhC, Rhe, Kid, Duffy, MN, P and others)
 * Drug induced immune mediated hemolytic anemia
 * Penicillin (high dose)
 * Methyldopa
 * Hemoglobinopathies (where these is an unstable or crystalline hemoglobin)
 * Paroxysmal nocturnal hemoglobinuria (rare acquired clonal disorder of red blood cell surface proteins)
 * Direct physical damage to RBCs
 * Microangiopathic hemolytic anemia
 * Secondary to artificial heart valve(s)
 * Aplastic anemia
 * Fanconi anemia
 * Diamond–Blackfan anemia (inherited pure red cell aplasia)
 * Acquired pure red cell aplasia
 * Decreased numbers of cells
 * Myelodysplastic syndrome
 * Myelofibrosis
 * Neutropenia (decrease in the number of neutrophils)
 * Agranulocytosis
 * Glanzmann's thrombasthenia
 * Thrombocytopenia (decrease in the number of platelets)
 * Idiopathic thrombocytopenic purpura (ITP)
 * Thrombotic thrombocytopenic purpura (TTP)
 * Heparin-induced thrombocytopenia (HIT)
 * Myeloproliferative disorders (Increased numbers of cells)
 * Polycythemia vera (increase in the number of cells in general)
 * Erythrocytosis (increase in the number of red blood cells)
 * Leukocytosis (increase in the number of white blood cells)
 * Thrombocytosis (increase in the number of platelets)
 * Myeloproliferative disorder
 * Transient myeloproliferative disease
 * Coagulopathies (disorders of bleeding and coagulation)
 * Thrombocytosis
 * Recurrent thrombosis
 * Disseminated intravascular coagulation
 * Disorders of clotting proteins
 * Hemophilia
 * Hemophilia A
 * Hemophilia B (also known as Christmas disease)
 * Hemophilia C
 * Von Willebrand disease
 * Disseminated intravascular coagulation
 * Protein S deficiency
 * Antiphospholipid syndrome
 * Disorders of platelets
 * Thrombocytopenia
 * Glanzmann's thrombasthenia
 * Wiskott–Aldrich syndrome

Hematological malignancies

 * Hematological malignancies
 * Lymphomas
 * Hodgkin's disease
 * Non-Hodgkin's lymphoma {includes the next five entries}
 * Burkitt's lymphoma
 * Anaplastic large cell lymphoma
 * Splenic marginal zone lymphoma
 * Hepatosplenic T-cell lymphoma
 * Angioimmunoblastic T-cell lymphoma (AILT)
 * Myelomas
 * Multiple myeloma
 * Waldenström macroglobulinemia
 * Plasmacytoma
 * Leukemias increased WBC
 * Acute lymphocytic leukemia (ALL)
 * Chronic lymphocytic leukemia (CLL){now included in theCLL/SCLL type NHL}
 * Acute myelogenous leukemia (AML)
 * Acute megakaryoblastic leukemia (AMKL), a sub-type of acute myelogenous leukemia
 * Chronic Idiopathic Myelofibrosis (MF)
 * Chronic myelogenous leukemia (CML)
 * T-cell prolymphocytic leukemia (T-PLL)
 * B-cell prolymphocytic leukemia (B-PLL)
 * Chronic neutrophilic leukemia (CNL)
 * Hairy cell leukemia (HCL)
 * T-cell large granular lymphocyte leukemia (T-LGL)
 * Aggressive NK-cell leukemia

Miscellaneous

 * Hemochromatosis
 * Asplenia
 * Hypersplenism
 * Gaucher's disease
 * Monoclonal gammopathy of undetermined significance
 * Hemophagocytic lymphohistiocytosis
 * Tempi syndrome

Hematological changes secondary to non-hematological disorders

 * Anemia of chronic disease
 * Infectious mononucleosis
 * AIDS
 * Malaria
 * Leishmaniasis