Henry Osborne

Henry Osborne may refer to:
 * Henry Osborne (American politician) (1751–1800), public official from Pennsylvania and Georgia
 * Henry Osborne (admiral) (1694–1771), British naval officer who served as Commodore Governor of Newfoundland
 * Sir Henry Osborne, 11th Baronet (1759–1837), Irish baronet and politician
 * Henry Osborne (Australian politician) (1803–1859), Australian pastoralist, collier and politician
 * Henry Osborne Havemeyer (1847–1907), American entrepreneur
 * Henry Z. Osborne (1848–1923), American Republican politician