Highwire

Highwire may refer to:


 * Highwire (protein)
 * "Highwire" (song), by the Rolling Stones (1991)
 * "Highwire", a song by Gin Blossoms on their 1996 album Congratulations I'm Sorry
 * "Highwired", a song by Nebula on their 2022 album Transmission from Mothership Earth