Holyoke (disambiguation)

Holyoke is a city in Hampden County, Massachusetts, United States.

Holyoke may also refer to:
 * Holyoke, Colorado, a home rule municipality in Phillips County, Colorado
 * Holyoke Publishing, an American comic book publisher
 * Holyoke Range, a traprock mountain range in Massachusetts
 * Mount Holyoke, a mountain in the Holyoke Range
 * Elizur Holyoke, namesake of Holyoke, Massachusetts
 * Keith Holyoake, a former Prime Minister of New Zealand
 * a fictional place
 * Holyoke station, an Amtrak station
 * Holyoke Heritage State Park
 * Holyoke Automobile Company