Homoaconitate hydratase

The enzyme homoaconitate hydratase catalyzes the chemical reaction


 * (1R,2S)-1-hydroxybutane-1,2,4-tricarboxylate $$\rightleftharpoons$$ (Z)-but-1-ene-1,2,4-tricarboxylate + H2O

This enzyme belongs to the family of lyases, specifically the hydro-lyases, which cleave carbon-oxygen bonds. The systematic name of this enzyme class is (1R,2S)-1-hydroxybutane-1,2,4-tricarboxylate hydro-lyase [(Z)-but-1-ene-1,2,4-tricarboxylate-forming]. Other names in common use include homoaconitase, cis-homoaconitase, HACN, Lys4, LysF, and 2-hydroxybutane-1,2,4-tricarboxylate hydro-lyase (incorrect). This enzyme participates in lysine biosynthesis.