Hopewell Presbyterian Church and Hopewell Cemetery

Hopewell Presbyterian Church and Hopewell Cemetery is a historic Presbyterian church and cemetery located at 5314 Old River Road in Florence, South Carolina. The two-story, frame, Greek Revival-style church was completed in 1842. It features a pedimented front gable end and two-story portico. It is clad in weatherboard and rests on a brick pier foundation with brick infill. The cemetery, in use since the late-18th century, occupies a three-acre site where the original Hopewell Presbyterian Church stood. It contains a notable collection of 19th century marble headstones and monuments. Inside the cemetery is the church's early Session House.

It was listed on the National Register of Historic Places in 2000.