Hutchinson's triad

Hutchinson's triad is named after Sir Jonathan Hutchinson (1828–1913). It is a common pattern of presentation for late congenital syphilis, and consists of three phenomena: interstitial keratitis, malformed teeth (Hutchinson incisors), and eighth nerve deafness. There may also be a deformity on the nose known as saddle nose deformity.

Interstitial keratitis is usually seen between five and twenty years of age. Damage to the teeth occurs in the first weeks after birth but is not seen until the first permanent teeth erupt around six years old. Eighth nerve deafness typically starts with high-frequency hearing loss between eight and ten years old, but can start at a younger age.