Hydroxylamine reductase (NADH)

In enzymology, a hydroxylamine reductase (NADH) is an enzyme that catalyzes the chemical reaction.


 * NH3 + NAD+ + H2O $$\rightleftharpoons$$ hydroxylamine + NADH + H+

The 3 substrates of this enzyme are NH3, NAD+, and H2O, whereas its 3 products are hydroxylamine, NADH, and H+.

This enzyme belongs to the family of oxidoreductases, specifically those acting on other nitrogenous compounds as donors with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is ammonium:NAD+ oxidoreductase. Other names in common use include hydroxylamine reductase, ammonium dehydrogenase, NADH-hydroxylamine reductase, N-hydroxy amine reductase, hydroxylamine reductase (NADH2), and NADH2:hydroxylamine oxidoreductase. This enzyme participates in nitrogen metabolism.